Aflibercept Beta (Genetical Recombination)



Aflibercept Beta is a recombinant fusion glycoprotein composed of the second immunoglobulin(Ig)-like C2 domain of the human vascular endothelial growth factor receptor (VEGFR) 1 in positions 1 – 104, the third Ig-like C2 domain of the human VEGFR 2 in positions 105 – 205, and the Fc domain of human IgG1 in positions 206 – 432. Aflibercept Beta is produced in Chinese hamster ovary cells. Aflibercept Beta is a glycoprotein (molecular weight: ca. 115,000) composed of 2 subunits consisting of 432 amino acid residues each.

[862111-32-8]