Batoclimab (Genetical Recombination)
Batoclimab is a recombinant anti-neonatal Fc receptor (FcRn) monoclonal antibody derived from IgG1, whose amino acid residues in the H-chain are substituted at 2 positions (L238A, L239A), and Lys at C-terminus is deleted. Batoclimab is produced in CHO cells. Batoclimab is a glycoprotein (molecular weight: ca. 146,000) composed of 2 H-chains (γ1-chains) consisting of 450 amino acid residues each and 2 L-chains (λ-chains) consisting of 214 amino acid residues each.
[2187430-05-1]
|