Bezlotoxumab (Genetical Recombination)



Bezlotoxumab is a recombinant human IgG1 monoclonal antibody against Clostridium difficile toxin B. Bezlotoxumab is produced in Chinese hamster ovary cells. Bezlotoxumab is a glycoprotein (molecular weight: ca. 148,000) composed of 2 H-chains (γ1-chains) consisting of 449 amino acid residues each and 2 L-chains (κ-chains) consisting of 215 amino acid residues each.

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