Bimekizumab (Genetical Recombination)
Bimekizumab is a recombinant humanized monoclonal antibody composed of complementarity-determining regions derived from rat anti-human interleukin-17A (IL-17A) and IL-17F monoclonal antibody, human framework regions and human IgG1 constant regions. Bimekizumab is produced in Chinese hamster ovary cells. Bimekizumab is a glycoprotein (molecular weight: ca.150,000) composed of 2 H-chains (γ1-chains) consisting of 455 amino acid residues each, and 2 L-chains (κ-chains) consisting of 214 amino acid residues each.
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