Caplacizumab (Genetical Recombination)



Caplacizumab is a recombinant single-chain bivalent monoclonal antibody (VH-VH) composed of variable regions of humanized anti-human von Willebrand factor (vWF) antibody at positions 1 – 128 and 132 – 259, whose complementarity-determining regions are derived from heavy-chain antibody from Lama glama. Caplacizumab is a protein consisting of 259 amino acid residues.

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