Cemiplimab (Genetical Recombination)



Cemiplimab is a recombinant anti-human PD-1 monoclonal antibody derived from human IgG4, whose amino acid residue at position 225 is substituted by Pro in the H-chain. Cemiplimab is produced in Chinese hamster ovary cells. Cemiplimab is a glycoprotein (molecular weight: ca. 147,000) composed of 2 H-chains (γ4-chains) consisting of 444 amino acid residues each and 2 L-chains (κ-chains) consisting of 214 amino acid residues each.

[1801342-60-8]