Cendakimab (Genetical Recombination)



Cendakimab is a recombinant anti-interleukin-13 monoclonal antibody whose complementarity-determining regions are derived from mouse antibody and other regions are derived from human IgG1. In the H-chain, the amino acid residues are substituted at 2 positions (L240A, L241A). Cendakimab is produced in CHO cells. Cendakimab is a glycoprotein (molecular weight: ca. 149,000) composed of 2 H-chains (γ1-chains) consisting of 453 amino acid residues each and 2 L-chains (κ-chains) consisting of 214 amino acid residues each.

[2151032-62-9]