Cetrelimab (Genetical Recombination)



Cetrelimab is a recombinant anti-PD-1 monoclonal antibody derived from human IgG4, whose amino acid residue in the H-chain is substituted at 1 position (S231P). Cetrelimab is produced in CHO cells. Cetrelimab is a glycoprotein (molecular weight: ca. 148,000) composed of 2 H-chains (γ4-chains) consisting of 450 amino acid residues each, and 2 L-chains (κ-chains) consisting of 214 amino acid residues each.

[2050478-92-5]