Clesrovimab (Genetical Recombination)



Clesrovimab is a recombinant anti-respiratory syncytial virus (RSV) F protein monoclonal antibody derived from human IgG1, whose amino acid residues in the H-chain are substituted at 3 positions (M262Y, S264T, T266E). Clesrovimab is produced in CHO cells. Clesrovimab is a glycoprotein (molecular weight: ca. 149,000) composed of 2 H-chains (γ1-chains) consisting of 457 amino acid residues each and 2 L-chains (κ-chains) consisting of 214 amino acid residues each.

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