Durvalumab (Genetical Recombination)



Durvalumab is a recombinant human IgG1 monoclonal antibody against human programmed cell death-ligand 1 (PD-L1). Durvalumab is produced in Chinese hamster ovary cells. Durvalumab is a glycoprotein (molecular weight : ca 149,000) composed of 2 H-chains (γ1-chains) consisting of 451 amino acid residues each and 2 L-chains (κ-chains) consisting of 215 amino acid residues each.

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