Efgartigimod Alfa (Genetical Recombination)



Efgartigimod Alfa is a recombinant human IgG1 Fc domain analog corresponding to amino acid residues at positions 221-447 (Eu numbering) of human IgG1, and the amino acid residues of Efgartigimod Alfa at positions 32, 34, 36, 213 and 214 are substituted by Tyr, Thr, Glu, Lys and Phe, respectively. Efgartigimod Alfa is produced in Chinese hamster ovary cells. Efgartigimod Alfa is a glycoprotein (molecular weight: ca. 54,000) composed of 2 subunits consisting of 227 amino acid residues each.

[1821402-21-4]