Elotuzumab (Genetical Recombination)



Elotuzumab is a recombinant humanized monoclonal antibody composed of complementarity-determining regions derived from mouse anti-human SLAM family member 7 (SLAMF7) monoclonal antibody and framework regions and constant regions derived from human IgG1. Elotuzumab is produced in mouse myeloma (NS0) cell line. Elotuzumab is a glycoprotein (molecular weight: ca. 148,000) composed of 2 H-chains (γ1-chains) consisting of 449 amino acid residues each and 2 L-chains (κ-chains) consisting of 214 amino acid residues each.

[915296-00-3]