Guselkumab (Genetical Recombination)
Guselkumab is a recombinant human IgG1 monoclonal antibody against human interleukin-23. Guselkumab is produced in Chinese hamster ovary cells. Guselkumab is a glycoprotein (molecular weight: ca. 146,000) composed of 2 H-chains (γ1-chains) consisting of 447 amino acid residues each and 2 L-chains (λ-chains) consisting of 217 amino acid residues each.
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