Insulin Efsitora Alfa (Genetical Recombination)



Insulin Efsitora Alfa is a recombinant fusion glycoprotein composed of human insulin B chain at positions 1 – 30, linker at positions 31 – 37, human insulin A chain at positions 38 – 58, linker at positions 59 – 78, and Fc domain of human IgG2 at positions 79 – 299, in which amino acid residues are substituted at 9 positions (Y16E, F25H, T27G, P28G, K29G, T30G, I47T, Y51D, N58G), and C-terminal Lys of the Fc domain is deleted. Insulin Efsitora Alfa is produced in CHO cells. Insulin Efsitora Alfa is a glycoprotein (molecular weight: ca. 67,000) composed of 2 subunits consisting of 299 amino acid residues each.

[2131038-11-2]