Insulin Glargine (Genetical Recombination) The Japanese Pharmacopoeia



Insulin Glargine (Genetical Recombination) is an analogue of human insulin (genetical recombination), being substituted asparagine residue with glycine residue at 21st of A chain and added two arginine residues at C-terminal of B chain. It is a peptide composed with A chain consisting of 21 amino acid residues and B chain consisting of 32 amino acid residues, and has an activity to reduce the blood glucose level.
It contains not less than 94.0% and not more than 105.0% of insulin glargine (genetical recombination) (C₂₆₇H₄₀₄N₇₂O₇₈S₆), calculated on the anhydrous basis. 0.0364 mg of Insulin Glargine (Genetical Recombination) is equivalent to 1 Insulin Unit.

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