Isatuximab (Genetical Recombination)



Isatuximab is a recombinant chimeric monoclonal antibody composed of variable regions derived from mouse anti-human CD38 antibody and constant regions derived from human IgG1. Isatuximab is produced in Chinese hamster ovary cells. Isatuximab is a glycoprotein (molecular weight: ca. 148,000) composed of 2 H-chains (γ1-chains) consisting of 450 amino acid residues each and 2 L-chains (κ-chains) consisting of 214 amino acid residues each.

[1461640-62-9]