Lonapegsomatropin (Genetical Recombination)



Lonapegsomatropin is a recombinant human growth hormone analogue, to which four methoxy polyethylene glycol polymers (total average molecular weight of the polymers: ca. 40,000) are bound via a cleavable linker (major pegylation sites: Lys residues). The protein moiety of Lonapegsomatropin is produced in Escherichia coli. Lonapegsomatropin is a pegylated protein (molecular weight: ca. 63,000) consisting of 191 amino acid residues.

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