Magrolimab (Genetical Recombination)



Magrolimab is a recombinant anti-CD47 monoclonal antibody whose complementarity-determining regions are derived from mouse antibody, and other regions are derived from human IgG4, whose amino acid residue in the H-chain is substituted at 1 position (S225P). Magrolimab is produced in CHO cells. Magrolimab is a glycoprotein (molecular weight: ca. 148,000) composed of 2 H-chains (γ4-chains) consisting of 444 amino acid residues each and 2 L-chains (κ-chains) consisting of 219 amino acid residues each.

[2169232-81-7]