Necitumumab (Genetical Recombination)



Necitumumab is a recombinant human IgG1 monoclonal antibody against human epidermal growth factor receptor. Necitumumab is produced in mouse myeloma (NS0) cells. Necitumumab is a glycoprotein (molecular weight: ca. 148,000) composed of 2 H-chains (γ1-chains) consisting of 451 amino acid residues each and 2 L-chains (κ-chains) consisting of 214 amino acid residues each.

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