Ozoralizumab (Genetical Recombination)



Ozoralizumab is a recombinant single-chain trivalent bispecific monoclonal antibody (VH-VH’-VH) composed of variable regions of humanized anti-human tumor necrosis factor α (TNF-α) antibody at positions 1 - 115 and 249 - 363, and a variable region of humanized anti-human serum albumin (HSA) antibody at positions 125 - 239, whose complementarity-determining regions are derived from heavy-chain antibody from Lama glama. Ozoralizumab is a protein consisting of 363 amino acid residues.

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