Pegcetacoplan



Pegcetacoplan is a PEGylated peptide (molecular weight: ca. 43,500) in which two identical synthetic peptides that bind to complement C3 are bound to each terminal of polyethylene glycol (molecular weight: ca. 39,600) via ε-amino group of C-terminal lysine amide. The peptide moiety consists of 15 amino acid residues. Chemical name is as follows:
O,O’-Bis[(S²,S¹²-cyclo{N-acetyl-L-isoleucyl-L-cysteinyl-L-valyl-1-methyl-L-tryptophyl-L-glutaminyl-L-α-aspartyl-L-tryptophylglycyl-L-alanyl-L-histidyl-L-arginyl-L-cysteinyl-L-threonyl-2-[2-(2-aminoethoxy)ethoxy]acetyl-L-lysinamide})-N^6.15-carbonyl]polyethylene glycol

[2019171-69-6]