Ramucirumab (Genetical Recombination)



Ramucirumab is a recombinant human IgG1 monoclonal antibody against the extracellular domain of the human vascular endothelial growth factor receptor-2. Ramucirumab is produced in mouse myeloma (NS0) cells. Ramucirumab is a glycoprotein (molecular weight: ca. 147,000) composed of 2 H-chains (γ1-chain) consisting of 446 amino acid residues each and 2 L-chains (κ-chain) consisting of 214 amino acid residues each.

[947687-13-0]