Romosozumab (Genetical Recombination)



Romosozumab is a recombinant humanized monoclonal antibody composed of complementarity-determining regions derived from mouse anti-human sclerostin monoclonal antibody and framework regions and constant regions derived from human IgG2. Romosozumab is produced in Chinese hamster ovary cells. Romosozumab is a glycoprotein (molecular weight: ca. 149,000) composed of 2H-chains (γ2-chains) consisting of 449 amino acid residues each and 2L-chains (κ-chains) consisting of 214 amino acid residues each.

[909395-70-6]