Sasanlimab (Genetical Recombination)



Sasanlimab is a recombinant anti-PD-1 monoclonal antibody whose complementarity-determining regions are derived from mouse antibody and other regions are derived from human IgG4. In the H-chain, the amino acid residue is substituted at 1 position (S225P). Sasanlimab is produced in CHO cells. Sasanlimab is a glycoprotein (molecular weight: ca. 149,000) composed of 2 H-chains (γ4-chains) consisting of 444 amino acid residues each and 2 L-chains (κ-chains) consisting of 220 amino acid residues each.

[2206792-50-7]