Sotatercept (Genetical Recombination)



Sotatercept is a recombinant fusion protein composed of an extracellular domain of human activin receptor type IIA at positions 1-115, linker at positions 116-119, and modified Fc domain of human IgG1 (A227V) at positions 120-334. Sotatercept is produced in CHO cells. Sotatercept is a glycoprotein (molecular weight: ca. 89,000) composed of 2 subunits consisting of 334 amino acid residues each.

[1001080-50-7]