Spesolimab (Genetical Recombination)



Spesolimab is a recombinant anti-human interleukin-36 receptor monoclonal antibody, the complementarity-determining regions of which are derived from mouse antibody and other regions are derived from human IgG1. Spesolimab is produced in Chinese hamster ovary cells. Spesolimab is a glycoprotein (molecular weight: ca. 149,000) composed of 2 H-chains (γ1-chains) consisting of 449 amino acid residues each and 2 L-chains (κ-chains) consisting of 215 amino acid residues each.

[2097104-58-8]