Tremelimumab (Genetical Recombination)



Tremelimumab is a recombinant human IgG2 monoclonal antibody against human cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4). Tremelimumab is produced in mouse myeloma (NS0) cells. Tremelimumab is a glycoprotein (molecular weight: ca. 149,000) composed of 2 H-chains (γ2-chains) consisting of 451 amino acid residues each and 2 L-chains (κ-chains) consisting of 214 amino acid residues each.

[745013-59-6]