Zilucoplan Sodium



Zilucoplan Sodium is tetrasodium salt of Zilucoplan. Zilucoplan is a chemically modified synthetic cyclic peptide that binds to human complement C5. The peptide moiety consists of 15 amino acid residues, and Lys residue at position 15 is modified. Chemical name is as follows:
Tetrasodium salt of N²-acetyl-L-lysyl-L-valyl-L-α-glutamyl-L-arginyl-L-phenylalanyl-L-α-aspartyl-N-methyl-L-α-aspartyl-3-methyl-L-valyl-L-tyrosyl-3-(1H-pyrrolo[2,3-b]pyridin-3-yl)-L-alanyl-L-α-glutamyl-L-tyrosyl-L-prolyl-(2S)-2-cyclohexylglycyl-N⁶-(3-{ω-[(N-hexadecanoyl-L-γ-glutamyl)amino]tetracosakis(oxyethylene)-α-yl}propanoyl)-L-lysine (6→1⁶)-lactam

C₁₇₂H₂₇₄N₂₄Na₄O₅₅  : 3650.10
[1841136-73-9 , Zilucoplan]