Zolbetuximab (Genetical Recombination)



Zolbetuximab is a recombinant chimeric monoclonal antibody composed of variable regions derived from mouse anti-human claudin-18 isoform 2 monoclonal antibody and constant regions derived from human IgG1. Zolbetuximab is produced in Chinese hamster ovary cells. Zolbetuximab is a glycoprotein (molecular weight: ca. 150,000) composed of 2 H-chains (γ1-chains) consisting of 448 amino acid residues each and 2 L-chains (κ-chains) consisting of 220 amino acid residues each.

[1496553-00-4]