ブロルシズマブ(遺伝子組換え)
Brolucizumab (Genetical Recombination)
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ブロルシズマブは,遺伝子組換え一本鎖抗体(scFv)であり,2-111 番目はヒト化抗ヒト血管内皮増殖因子(VEGF)モノクローナル抗体のL 鎖の可変領域,133-252 番目はヒト化抗ヒトVEGF モノクローナル抗体のH 鎖の可変領域からなる.ブロルシズマブは,252 個のアミノ酸残基からなるタンパク質である.
Brolucizumab is a recombinant single-chain antibody (scFv) composed of variable regions of an L-chain derived from humanized anti-human vascular endothelial growth factor (VEGF) monoclonal antibody at positions 2-111, and an H-chain derived from humanized anti-human VEGF monoclonal antibody at positions 133-252. Brolucizumab is a protein consisting of 252 amino acid residues.
[1531589-13-5]
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