化合物1


{(2R,4aS,6S,7R,8S,8aS)-7,8-ビス{[(1,1-ジメチルエチル)ジメチルシリル]オキシ}-6-[(1S,2E)-1-{[(1,1-ジメチルエチル)ジメチルシリル]オキシ}-3-ヨードプロパ-2-エン-1-イル]オクタヒドロピラノ[3,2-b]ピラン-2-イル}酢酸メチル

Methyl{(2R,4aS,6S,7R,8S,8aS)-7,8-bis{[(1,1-dimethylethyl)dimethylsilyl]oxy}-6-[(1S,2E)-1-{[(1,1-dimethylethyl)dimethylsilyl]oxy}-3-iodoprop-2-en-1-yl]octahydropyrano[3,2-b]pyran-2-yl}acetate

化合物2


3-[(2S,5S)-5-{2-[(2S,4R,6R)-6-({(2S,3S,4R,5R)-5-[(2S)-2,3-ビス{[(1,1-ジメチルエチル)ジメチルシリル]オキシ}プロピル]-4-メトキシ-3-[(フェニルスルホニル)メチル]テトラヒドロフラン-2-イル}メチル)-4-メチル-5-メチリデンテトラヒドロ-2H-ピラン-2-イル]エチル}-4-メチリデンテトラヒドロフラン-2-イル]プロパン-1-オール

3-[(2S,5S)-5-{2-[(2S,4R,6R)-6-({(2S,3S,4R,5R)-5-[(2S)-2,3-Bis{[(1,1-dimethylethyl)dimethylsilyl]oxy}propyl]-4-methoxy-3-[(phenylsulfonyl)methyl]tetrahydrofuran-2-yl}methyl)-4-methyl-5-methylidenetetrahydro-2H-pyran-2-yl]ethyl}-4-methylidenetetrahydrofuran-2-yl]propan-1-ol

類縁物質A


(1R,3S,8S,11S,14S,16R,18R,20S,22R,23R, 24S,28R,31S,33S,34R,35S,37S)-22-[(2S)-3-アミノ-2-ヒドロキシプロピル]-34,37-ジヒドロキシ-23-メトキシ-16-メチル-10,17-ジメチリデン-2,21,32,36,38,39-ヘキサオキサヘプタシクロ[26.6.2.1^3,33.1^8,11.1^14,18.0^20,24.0^31,35]ノナトリアコンタン-5,26-ジオン

(1R,3S,8S,11S,14S,16R,18R,20S,22R,23R,24S,28R,31S,33S,34R,35S,37S)-22-[(2S)-3-Amino-2-hydroxypropyl]-34,37-dihydroxy-23-methoxy-16-methyl-10,17-dimethylidene-2,21,32,36,38,39-hexaoxaheptacyclo[26.6.2.1^3,33.1^8,11.1^14,18.0^20,24.0^31,35]nonatriacontane-5,26-dione

類縁物質B


(2R,3R,3aS,7R,8aS,9S,10aR,11S,12R,13aR, 13bS,15S,18S,21S,24S,26R,28R,29aS)-2-[(2R)-3-アミノ-2-ヒドロキシプロピル]-3-メトキシ-26-メチル-20,27-ジメチリデンヘキサコサヒドロ-11,15:18,21:24,28-トリエポキシ-7,9-エタノ-12,15-メタノ-9H,15H-フロ[3,2-i]フロ[2',3':5,6]ピラノ[4,3-b][1,4]ジオキサシクロペンタコシン-5(4H)-オン

(2R,3R,3aS,7R,8aS,9S,10aR,11S,12R,13aR,13bS,15S,18S,21S,24S,26R,28R,29aS)-2-[(2R)-3-Amino-2-hydroxypropyl]-3-methoxy-26-methyl-20,27-dimethylidenehexacosahydro-11,15:18,21:24,28-triepoxy-7,9-ethano-12,15-methano-9H,15H-furo[3,2-i]furo[2',3':5,6]pyrano[4,3-b][1,4]dioxacyclopentacosin-5(4H)-one

類縁物質C


(2R,3R,3aS,7R,8aS,9S,10aR,11S,12R,13aR, 13bS,15S,18S,21S,24S,26R,28R,29aS)-2-[(2R)-2-アミノ-3-ヒドロキシプロピル]-3-メトキシ-26-メチル-20,27-ジメチリデンヘキサコサヒドロ-11,15:18,21:24,28-トリエポキシ-7,9-エタノ-12,15-メタノ-9H,15H-フロ[3,2-i]フロ[2',3':5,6]ピラノ[4,3-b][1,4]ジオキサシクロペンタコシン-5(4H)-オン

(2R,3R,3aS,7R,8aS,9S,10aR,11S,12R,13aR,13bS,15S,18S,21S,24S,26R,28R,29aS)-2-[(2R)-2-Amino-3-hydroxypropyl]-3-methoxy-26-methyl-20,27-dimethylidenehexacosahydro-11,15:18,21:24,28-triepoxy-7,9-ethano-12,15-methano-9H,15H-furo[3,2-i]furo[2',3':5,6]pyrano[4,3-b][1,4]dioxacyclopentacosin-5(4H)-one

類縁物質D


(1R,2S,3S,4S,5S,6R,11S,14S,17S,19R,21R, 23S,25R,26R,27S,31R,34S)-25-[(2S)-3-アミノ-2-ヒドロキシプロピル]-2,5-ジヒドロキシ-26-メトキシ-19-メチル-13,20-ジメチリデン-24,35,36,37,38,39-ヘキサオキサヘプタシクロ[29.3.1.1^3,6.1^4,34.1^11,14.1^17,21.0^23,27]ノナトリアコンタン-8,29-ジオン

(1R,2S,3S,4S,5S,6R,11S,14S,17S,19R,21R,23S,25R,26R,27S,31R,34S)-25-[(2S)-3-Amino-2-hydroxypropyl]-2,5-dihydroxy-26-methoxy-19-methyl-13,20-dimethylidene-24,35,36,37,38,39-hexaoxaheptacyclo[29.3.1.1^3,6.1^4,34.1^11,14.1^17,21.0^23,27]nonatriacontane-8,29-dione

類縁物質E


(1R,2S,3S,4S,5S,6S,11S,14S,17S,19R,21R,23S, 25R,26R,27S,31R,34S)-25-[(2S)-3-アミノ-2-ヒドロキシプロピル]-2,5-ジヒドロキシ-26-メトキシ-19-メチル-13,20-ジメチリデン-24,35,36,37,38,39-ヘキサオキサヘプタシクロ[29.3.1.1^3,6.1^4,34.1^11,14.1^17,21.0^23,27]ノナトリアコンタン-8,29-ジオン

(1R,2S,3S,4S,5S,6S,11S,14S,17S,19R,21R,23S,25R,26R,27S,31R,34S)-25-[(2S)-3-Amino-2-hydroxypropyl]-2,5-dihydroxy-26-methoxy-19-methyl-13,20-dimethylidene-24,35,36,37,38,39-hexaoxaheptacyclo[29.3.1.1^3,6.1^4,34.1^11,14.1^17,21.0^23,27]nonatriacontane-8,29-dione

類縁物質F


(2R,3R,3aS,7R,8aS,9S,10aR,11S,12R,13aR,13bS,15S,18S,21S,24S,26R,28R,29aS)-2-[(2S)-2,3-ジヒドロキシプロピル]-3-メトキシ-26-メチル-20,27-ジメチリデンヘキサコサヒドロ-11,15:18,21:24,28-トリエポキシ-7,9-エタノ-12,15-メタノ-9H,15H-フロ[3,2-i]フロ[2',3':5,6]ピラノ[4,3-b][1,4]ジオキサシクロペンタコシン-5(4H)-オン

(2R,3R,3aS,7R,8aS,9S,10aR,11S,12R,13aR,13bS,15S,18S,21S,24S,26R,28R,29aS)-2-[(2S)-2,3-Dihydroxypropyl]-3-methoxy-26-methyl-20,27-dimethylidenehexacosahydro-11,15:18,21:24,28-triepoxy-7,9-ethano-12,15-methano-9H,15H-furo[3,2-i]furo[2',3':5,6]pyrano[4,3-b][1,4]dioxacyclopentacosin-5(4H)-one